T 1303/18 - Disclosure of a compound, inherency for Art.54 and Art.123(2)

Key points

• The question is whether the priority is valid.
• "The appellant [proprietor] argued that there was no doubt that the claims as granted and the whole disclosure of [priority application] D49 concerned the same invention within the meaning of Article 87(1) EPC and opinion G 2/98, namely, polymorphic form II of rotigotine."
• "In claim 1 as granted (point II above), the claimed compound is said to be polymorphic form II of rotigotine and is defined by at least one of four properties, namely: (a) a certain X-ray powder diffraction spectrum comprising four peaks with an error margin of ± 0.2, said to be measured with Cu-Kalpha irradiation (1.54060 Å); (b) a Raman spectrum comprising specific peaks with an error margin of ± 3 cm**(-1); (c) a DSC peak with a certain Tonset with an error margin of ± 2°C; (d) [a melting point of 97°C ± 2°C]."
• The Board: "Comparing the definition in terms of property (a) given in claim 1 as granted with the above disclosures in D49 reveals the following differences. - The set of peaks defined for the X-ray powder diffraction spectrum in claim 1 as granted is a set of four peaks, while that in the above disclosures of D49 is a set of 14 peaks. 
• The Board also considers property (b) (Raman spectrum), finding differences; the same applies for properties (c) and (d).
• As to the melting point:  "The melting point is not disclosed [in D49]" ... "no basis exists in D49 for  a melting point of 97°C ± 2°C as defined in claim 1 as granted"
• " in the current case, it is the subject-matter of claim 1 as granted that has to be directly and unambiguously derivable from D49. The appellant [proprietor] pointed out that the patent and D49 disclosed the same methods for characterising the mentioned polymorphic form and that the same figures resulted from this characterisation, thus demonstrating identity of the invention. However, the fact that the same characterisation methods like X-ray diffraction, Raman spectrum and DSC calorimetry are used to describe the disclosed compound in both the patent and D49 plays no role when assessing the above requirement. Also the fact that the patent and D49 share the same figures is irrelevant; what is decisive is whether or not, using common general knowledge, a compound as defined in claim 1 of the patent is directly and unambiguously disclosed in D49 as a whole."
• " The appellant argued that identity between the claimed compound and the compound disclosed in D49 was already evident from the fact that the polymorphic form of rotigotine was designated as form II in both claim 1 as granted and D49. While alleged discrepancies in the definition of form II were merely due to the different sets of analytical data used for defining form II, this did not change the fact that the same compound was disclosed. A polymorphic form of a given compound remained the same regardless of the method used for characterising it."
• "Contrary to the appellant's view, it is the set of analytical data chosen to characterise the compound that gives the skilled person the information necessary to identify the compound referred to. For the reasons set out above, the set of analytical data used in claim 1 as granted is not directly and unambiguously disclosed in D49. Therefore, it cannot be concluded that the compound defined in claim 1 as granted is the same compound as disclosed in D49."
• "the appellant submitted that structural properties allegedly lacking in D49 were implicitly disclosed to the skilled person since they were inherent to polymorphic form II and accessible by using the disclosed analytical methods. "
• As a comment, this argument may run foul of the rule that amendments may not add technical information (G2/10 r.4.5.1). Even if a compound inherently exhibits a  melting point of 97°C, adding a statement to that effect to a patent text may still violate Art. 123(2). However, this position may be controversial. A possible counter-argument could be that there is no change of subject-matter because there is only a single compound "rotigotine form II". This raises, in turn, the epistemological question of what is a compound? And what is the scope of a patent claim directed to a particular polymorphic form of a compound, and how this scope depends on the definition of the polymorphic form? 
• "This argument is not convincing either. Priority has been claimed from a written disclosure (D49) and it is from this disclosure that the skilled person should have been able, at the relevant date, to derive directly and unambiguously, using common general knowledge, the subject-matter of claim 1 as granted. However, as set out above, D49 does not disclose the same compound as that defined in claim 1 as granted."
• "Moreover, even assuming that the skilled person could have been in a position to analyse a sample of the rotigotine form II disclosed in D49, the skilled person would have obtained, inter alia, the whole X-ray powder diffraction spectrum and Raman spectrum (which are in fact represented in figures 1 and 5 of D49). However, for the reasons given above, these whole spectra do not constitute an adequate basis for the definition of the polymorphic form of rotigotine as given in claim 1 as granted. "
• "the board sees no inconsistency in the way the opposition division assessed the validity of priority on one hand and the novelty of the claimed subject-matter on the other. In fact, in terms of novelty (see corresponding point below), the relevant prior art is a sample of a polymorphic form of rotigotine, which could have been analysed by the skilled person so as to obtain, inter alia, its whole X-ray powder diffraction spectrum and Raman spectrum. These whole spectra were found by the opposition division to anticipate the definition of the polymorphic form of rotigotine as given in claim 1 as granted."
• "The application of one and the same standard for Articles 54 and 87 EPC does not, however, mean that the conclusions for novelty and validity of priority must necessarily be the same. More specifically, [] a priority application can directly and unambiguously disclose something falling within the scope of a claim of a subsequent application and thus anticipate the subject-matter of this claim while at the same time the latter still includes subject-matter not disclosed in the priority application, such that the priority is invalid."
• In the case at hand, the priority application was not published and not cited as novelty-destroying, so the Board is considering a hypothetical novelty objection if D49 was prior art. Indeed, the compound disclosed in D49 would inherently have the melting point specified in claim  1 (leaving aside that claim 1 specifies four alternative features) and hence inherently fall within the scope of the claim even if D49 does not disclose the melting point.
• The OD had found that: "The subject-matter of claim 1 of the main request and claim 1 of auxiliary requests 1 and 2 was not novel over the public prior use of rotigotine form II in commercial Neupro**(®) patches which occurred between the earliest and the subsequent priority date."

Partial priority / admissibility

• The Board did not admit the argument based on partial priority:  "In its letter dated 21 August 2020 (point 1.2.1.3 on pages 11 to 14), i.e. after the filing of the grounds of appeal and replies and before the summons to oral proceedings was issued (6 December 2021), the appellant argued for the first time that, should the priority from D49 be considered invalid, the subject-matter of claim 1 as granted should at least be entitled to a partial priority from D49 in accordance with decision G 1/15." The Board: "Decision G 1/15 was published in the Official Journal of the EPO in 2017, i.e. before the oral proceedings held on 15 February 2018 before the opposition division. Therefore, the appellant's defence claiming a right to partial priority could and should have been presented before the opposition division or included at the latest in the statement of grounds of appeal, so as to comply with the requirement to present the complete case at the outset of the appeal proceedings."
• " In its letter dated 21 August 2020, the appellant did not indicate any reason why the defence asserting a right to partial priority was only filed after its statement of grounds of appeal."
•  "The appellant [proprietor] argued that this defence did not constitute an amendment of its appeal case. It only concerned interpretation of law by means of an argument based on a decision of the Enlarged Board of Appeal. Therefore, the appellant was allowed to make this defence at any point during the proceedings. "
• " Contrary to the appellant's view, the defence by which a right to partial priority was invoked was not merely a presentation of a new argument pertaining to the interpretation of law but comprised a new allegation of fact. The appellant namely asserted that priority application D49 directly and unambiguously disclosed in an enabling manner part of the subject-matter of claim 1 as granted, and specifically that claim 1 as granted encompassed this part as an alternative subject-matter by virtue of a "generic "OR"-claim" within the meaning of decision G 1/15 (order). Therefore, the submitted defence would have involved a new factual assessment of the subject-matter of claim 1 as granted and of priority application D49, namely as to precisely which part of claim 1 it was that allegedly enjoyed partial priority and where it was disclosed in D49."
• " As pointed out by the respondents, this new factual assessment would have been complex. This was evident from the fact that in some aspects the subject-matter of claim 1 as granted had been restricted as compared with the disclosure in D49 by inserting characteristics of the claimed compound such as a melting point and further Raman peaks which were not disclosed in D49. 
• As a comment, as the public prior use is full prior art (Art.54(2)) for those parts of the claim for which the priority is invalid, the prima facie relevance of the arguments is not entirely clear. 

EPO 

The link to the decision is provided after the jump, as well as (an extract of) the text of the decision.

https://www.epo.org/law-practice/case-law-appeals/recent/t181303eu1.html

Reasons for the Decision

Main request and main substantive request - the patent as granted - claim 1 - validity of the earliest priority under Article 87(1) EPC

1. The patent was granted with an earliest priority date of 28 November 2007 claimed from applications D48 and D49 filed on the same day. It is common ground that the content of these two priority applications is identical. For ease of reference, the board refers hereinafter only to D49.

1.1 The respondents objected to the validity of this earliest priority. They argued that the subject-matter of claim 1 as granted was not directly and unambiguously disclosed in D49. They referred to opinion G 2/98.

1.2 The appellant argued that there was no doubt that the claims as granted and the whole disclosure of D49 concerned the same invention within the meaning of Article 87(1) EPC and opinion G 2/98, namely, polymorphic form II of rotigotine.

2. The board disagrees with the appellant for the following reasons.

2.1 As set out in opinion G 2/98 (OJ EPO 2001, page 413, Conclusion), the "requirement for claiming priority of 'the same invention', referred to in Article 87(1) EPC, means that priority of a previous application in respect of a claim in a European patent application in accordance with Article 88 EPC is to be acknowledged only if the skilled person can derive the subject-matter of the claim directly and unambiguously, using common general knowledge, from the previous application as a whole" (emphasis added by the board).

2.2 Therefore, in the current case, it is the subject-matter of claim 1 as granted that has to be directly and unambiguously derivable from D49. The appellant pointed out that the patent and D49 disclosed the same methods for characterising the mentioned polymorphic form and that the same figures resulted from this characterisation, thus demonstrating identity of the invention. However, the fact that the same characterisation methods like X-ray diffraction, Raman spectrum and DSC calorimetry are used to describe the disclosed compound in both the patent and D49 plays no role when assessing the above requirement. Also the fact that the patent and D49 share the same figures is irrelevant; what is decisive is whether or not, using common general knowledge, a compound as defined in claim 1 of the patent is directly and unambiguously disclosed in D49 as a whole. In this respect, it should further be recalled that the disclosure as the basis for the right to priority under Article 87(1) EPC and as the basis for amendments in an application under Article 123(2) EPC has to be interpreted in the same way (decision G 1/03, OJ EPO 2004, 413, point 4 of the reasons and G 2/10, OJ EPO 2012, 376, point 4.3 of the reasons).

2.3 In claim 1 as granted (point II above), the claimed compound is said to be polymorphic form II of rotigotine and is defined by at least one of four properties, namely:

(a) a certain X-ray powder diffraction spectrum comprising four peaks with an error margin of ± 0.2, said to be measured with Cu-Kalpha irradiation (1.54060 Å);

(b) a Raman spectrum comprising specific peaks with an error margin of ± 3 cm**(-1);

(c) a DSC peak with a certain Tonset with an error margin of ± 2°C;

(d) a certain melting point with an error margin of ± 2°C.

2.4 As regards property (a), D49 discloses a polymorphic form of rotigotine, named "form (II)", defined in claim 1 of D49 as being characterised by "any one, any two, any three, any four or more of the powder X-ray diffraction peaks including, but not limited to: 12.04, 12.32, 12.97, 13.68, 17.13, 17.72, 19.01, 20.40, 20.52, 21.84, 21.96, 22.01, 22.91 and 22.96 ±0.1 (°2theta)" (emphasis added by the board). The same disclosure is found on page 3, lines 14 to 20, and page 6, lines 3 to 9, of D49. Figure 1 of D49 shows the powder X-ray diffractogram of the polymorphic "form II" of rotigotine according to D49. The "main peaks" according to figure 1 are stated in D49, page 11, lines 20 to 26, to be at diffraction angles (°2theta) of 12.04, 12.32, 12.97, 13.68, 17.13, 17.72, 19.01, 20.40, 20.52, 21.84, 21.96, 22.01, 22.91 and 22.96. These angles are identical to those cited in claim 1, page 3, lines 14 to 20, and page 6, lines 3 to 9, of D49.

2.4.1 Comparing the definition in terms of property (a) given in claim 1 as granted with the above disclosures in D49 reveals the following differences.

- The set of peaks defined for the X-ray powder diffraction spectrum in claim 1 as granted is a set of four peaks, while that in the above disclosures of D49 is a set of 14 peaks.

- The X-ray powder diffraction spectrum according to claim 1 as granted must comprise all of the peaks mentioned in this claim (i.e. four peaks), while the above disclosures of D49 allow the spectrum to comprise only one, only two or only three of the peaks comprised in the set of peaks defined in these disclosures (see highlighted part above).

- An error margin of ±0.2 is cited in claim 1 as granted for the mentioned X-ray diffraction peaks, while an error margin of ±0.1 is given in the above disclosures of D49 (see highlighted part above).

2.4.2 It follows that, in order to arrive at the four peaks stated in claim 1 as granted, at least two selections within D49 are needed: a first selection for defining the compound of D49 by means of a number of four peaks within the X-ray powder diffraction spectrum; and a second selection for arriving at the specific diffraction angles (°2theta) mentioned in claim 1 as granted for these four peaks. However, D49 contains no pointer towards these two specific selections.

2.4.3 Additionally, claim 1 as granted defines the four mentioned peaks with an error margin of ±0.2. This margin has been broadened as compared with the error margin of ±0.1 disclosed in D49 (see above). This means that, according to claim 1 as granted, the peaks can be shifted so that they no longer match the diffraction angles (°2theta) disclosed in D49. No disclosure of this broadening of the error margin can be found in D49.

2.4.4 Therefore, the skilled person, at the relevant date of the subsequent filing, would not have derived a compound as defined by the X-ray powder diffraction spectrum mentioned in claim 1 as granted directly and unambiguously, using common general knowledge, from the disclosure in D49.

2.4.5 The appellant referred to decision T 517/14, especially to point 5.4 of the reasons, which, in its view, confirmed that by mentioning in the claim five peaks of the X-ray powder diffraction reflections, the crystalline form of the claimed compound was defined in a unique way.

However, decision T 517/14 does not change the board's conclusion set out above. According to point 5.4 of the reasons referred to by the appellant, the entrusted board held that no evidence had been provided by the opponent that the five peaks of X-ray reflections used in claim 1 at issue for characterising the claimed compound (point I of T 517/14) were not sufficient to define the crystalline form of the claimed compound in a unique way. However, in the current case, it is not in dispute that the peaks of the X-ray diffraction spectrum mentioned in claim 1 as granted are suitable for defining the claimed compound. What is decisive is that, for the reasons set out in the present decision, the claimed compound is not the same as that directly and unambiguously disclosed in priority application D49.

2.5 As regards property (b) (Raman spectrum), D49 discloses a polymorphic form of rotigotine, named "form II", defined in claim 3 of D49 as being characterised by "its Raman spectrum with main peaks at the following wave numbers (cm**(-1)): 226.2, 297.0, 710.0, 737.3, 750.8, 847.3, 878.3, 1018.7, 1075.6, 1086.2, 1214.3, 1255.1, 1330.7, 1354.3 and 1448.7 ± 1 cm**(-1)" (emphasis added by the board). The same disclosure, with the addition of a main peak at 743.3 cm**(-1), is found on page 3, lines 22 to 26, and, with reference to figure 5, on page 12, lines 1 to 11, of D49.

2.5.1 When comparing the definition in terms of property (b) given in claim 1 as granted with the above disclosures in D49, it is noted that claim 1 as granted mentions two additional peaks at 363.9 and 1278.2 cm**(-1). A peak at 363.9 cm**(-1) is indicated in figure 5 of D49 representing the full Raman spectrum of form II of rotigotine according to D49. However, this peak is here shown together with a vast number of other peaks which are not mentioned in the above disclosures in claim 3 and on pages 3 and 12 of D49. As regards the peak at 1278.2 cm**(-1), this is not indicated in figure 5 of D49.

2.5.2 Additionally, claim 1 as granted defines the recited peaks with an error margin of ±3 cm**(-1). This margin has been broadened as compared with the error margin of ±1 cm**(-1) disclosed in D49 (see highlighted part above). This means that, according to claim 1 as granted, the peaks can be shifted so that they no longer match the wave numbers disclosed in D49. No disclosure of this broadening of the error margin can be found in D49.

2.5.3 As a consequence, the skilled person, at the relevant date of the subsequent filing, would not have derived the Raman spectrum as defined in claim 1 as granted directly and unambiguously, using common general knowledge, from the disclosure in D49.

2.6 As regards properties (c) and (d) (DSC peak and melting point), D49 (page 12, lines 16 to 34, and figure 7) discloses a DSC analysis carried out on rotigotine form II according to D49 by using a heating rate of 10°C/min. An onset at 97.30°C is reported, while the melting point is not disclosed.

When comparing the definitions in terms of properties (c) and (d) given in claim 1 as granted with the above disclosures in D49, no basis exists in D49 for a broader onset at 97°C ± 2°C and a melting point of 97°C ± 2°C as defined in claim 1 as granted.

2.7 Thus, it follows that the definition given for the compound referred to in granted claim 1 differs in numerous aspects from that disclosed in priority application D49. As a consequence, it cannot be concluded that the compound of granted claim 1 is the same as that disclosed in D49.

2.8 The appellant argued that identity between the claimed compound and the compound disclosed in D49 was already evident from the fact that the polymorphic form of rotigotine was designated as form II in both claim 1 as granted and D49. While alleged discrepancies in the definition of form II were merely due to the different sets of analytical data used for defining form II, this did not change the fact that the same compound was disclosed. A polymorphic form of a given compound remained the same regardless of the method used for characterising it.

2.9 This argument is not convincing. The common designation as "polymorphic form II of rotigotine" in both claim 1 as granted and D49 is not sufficient to conclude that the same compound as disclosed in D49 is defined in claim 1 as granted. In fact, the mere name "polymorphic form II of rotigotine" does not give the skilled person any information as regards the identity of the compound. Contrary to the appellant's view, it is the set of analytical data chosen to characterise the compound that gives the skilled person the information necessary to identify the compound referred to. For the reasons set out above, the set of analytical data used in claim 1 as granted is not directly and unambiguously disclosed in D49. Therefore, it cannot be concluded that the compound defined in claim 1 as granted is the same compound as disclosed in D49.

2.10 The appellant further submitted that only form I and form II of rotigotine were known at the earliest priority date and form II was clearly distinguished from form I. Stating that the priority from D49 was not valid amounted to insinuating that a third polymorphic form of rotigotine existed but this was clearly wrong.

2.11 However, the board concurs with the respondents that by accepting this argument, the earliest priority would become retroactively invalid if another crystal form of rotigotine was discovered later, which would fall under the definition given in claim 1 as granted but not under the disclosure of D49. Hence, this argument runs against the principle of legal certainty and must thus fail.

2.12 The appellant also argued that the respondents bore the burden of proving that claim 1 as granted defined a compound different from the one disclosed in D49. No evidence in this respect had been presented.

2.13 However, it was the appellant (patent proprietor) who introduced various differences (see above) between the compound defined in granted claim 1 and that disclosed in D49. If, despite these differences, the appellant asserts that the compound of granted claim 1 is the same as that disclosed in D49, it is the appellant who bears the burden of proving this. In fact, it is for an applicant to ensure, where priority from a previous application is claimed, that the same invention is defined, according to the required standard, in the subsequent application as filed.

2.14 Additionally, the appellant submitted that structural properties allegedly lacking in D49 were implicitly disclosed to the skilled person since they were inherent to polymorphic form II and accessible by using the disclosed analytical methods. In this respect, the appellant further submitted that in the appealed decision the opposition division inconsistently applied two different standards for the assessment of the validity of the earliest priority on the one hand and novelty on the other hand. With respect to novelty, the mere reference to "polymorphic form II" of rotigotine in the prior art was sufficient to assume a novelty-destroying disclosure. On the other hand, the opposition division objected to a missing or slightly differing reproduction of the analytical data of granted claim 1 in D49 in a 1:1 manner and denied the disclosure in D49 of polymorphic form II of rotigotine as defined in granted claim 1 despite the fact that claim 1 as granted explicitly referred to "polymorphic form II" of rotigotine.

2.15 This argument is not convincing either. Priority has been claimed from a written disclosure (D49) and it is from this disclosure that the skilled person should have been able, at the relevant date, to derive directly and unambiguously, using common general knowledge, the subject-matter of claim 1 as granted. However, as set out above, D49 does not disclose the same compound as that defined in claim 1 as granted.

2.16 Moreover, even assuming that the skilled person could have been in a position to analyse a sample of the rotigotine form II disclosed in D49, the skilled person would have obtained, inter alia, the whole X-ray powder diffraction spectrum and Raman spectrum (which are in fact represented in figures 1 and 5 of D49). However, for the reasons given above, these whole spectra do not constitute an adequate basis for the definition of the polymorphic form of rotigotine as given in claim 1 as granted. For this reason, the board sees no inconsistency in the way the opposition division assessed the validity of priority on one hand and the novelty of the claimed subject-matter on the other. In fact, in terms of novelty (see corresponding point below), the relevant prior art is a sample of a polymorphic form of rotigotine, which could have been analysed by the skilled person so as to obtain, inter alia, its whole X-ray powder diffraction spectrum and Raman spectrum. These whole spectra were found by the opposition division to anticipate the definition of the polymorphic form of rotigotine as given in claim 1 as granted.

2.17 For these reasons, the board concludes that the subject-matter of claim 1 as granted does not enjoy the claimed earliest priority date of 28 November 2007 (Article 87(1) EPC and Article 89 EPC). Therefore, the earliest priority is not valid.

2.18 This conclusion is in line with decision T 1684/16 (points 2.1 to 2.5 of the reasons) concerning the ground for opposition under Article 100(c) EPC. The entrusted board found that the definition contained in granted claim 1 at issue of a polymorphic form I of a certain compound as five specific peaks of the X-ray diffraction pattern was not directly and unambiguously disclosed in the application as filed. Even though the latter disclosed a polymorphic form bearing the same name ("Form I"), this form was stated to be characterised by at least one of fifteen or twenty-four peaks. By analogy with the case at hand, the entrusted board found that the application as filed provided no teaching pointing to the selection of the five peaks mentioned in the claim at issue. The granted claim at issue therefore contained subject-matter extending beyond the content of the application as filed (Article 100(c) EPC). This conclusion, which implies that the claimed subject-matter lacks proper basis in the application as filed, is analogous to that drawn in the current case, namely that the subject-matter of claim 1 as granted is not based on priority application D49.

Referral of specific questions to the Enlarged Board of Appeal - Article 112(1)(a) EPC

3. The appellant requested, should the board envisage denying validity of the earliest priority, that specific questions (point XIII above) be referred to the Enlarged Board of Appeal. It argued that there was otherwise a risk of a contradiction between the case law on novelty and that on validity of priority and that the unitary concept of disclosure would be violated. In this regard, the appellant referred to section I.C.6.2 of the publication Case Law of the Boards of Appeal, mentioning, inter alia, decision T 12/81, and stated that there was no doubt that priority application D49 would have been considered novelty-destroying for the subject-matter of claim 1 as granted.

4. The board finds these arguments unconvincing. As is derivable from each of the proposed questions (point XIII above), the request for a referral to the Enlarged Board of Appeal rests on the precondition that the same polymorphic form is defined in both the claim at issue and the priority application. However, for the reasons given above, the board has concluded that the polymorphic form defined in claim 1 as granted is not directly and unambiguously disclosed in the priority application D49. Therefore, what is claimed is not the same compound and the precondition for the questions to be referred according to the appellant is not met. Thus, the proposed questions, or answers thereto, respectively, would not have been pertinent for deciding the present case.

4.1 Furthermore, contrary to the appellant's view, no violation of the general principle of direct and unambiguous disclosure common to the assessment of compliance with Articles 123(2), 54 and 87(1) EPC derives from the board's conclusion above. In fact, it is acknowledged that the standard to be applied when deciding what an item of prior art and a priority application disclose must be the same for Articles 54 and 87 EPC. This standard is the gold standard established in decision G 2/10 and uses the test of direct and unambiguous disclosure. The application of one and the same standard for Articles 54 and 87 EPC does not, however, mean that the conclusions for novelty and validity of priority must necessarily be the same. More specifically, as set out by the respondents during the oral proceedings, a priority application can directly and unambiguously disclose something falling within the scope of a claim of a subsequent application and thus anticipate the subject-matter of this claim while at the same time the latter still includes subject-matter not disclosed in the priority application, such that the priority is invalid.

4.2 The board's conclusion is also not in contradiction to the passage in section I.C.6.2 of the publication Case Law of the Boards of Appeal referred to by the appellant. By referring to landmark decision T 12/81 (OJ EPO 1982, page 296), this passage states that "If a product cannot be defined by a sufficiently accurate generic formula, it is permissible to make the definition more precise by additional product parameters such as melting point, hydrophilic properties, NMR coupling constant or the method of preparation (product-by-process claims). From this it necessarily follows that patent documents using such definitions will be prejudicial to the novelty of later applications claiming the same substance defined in a different and perhaps more precise way" (emphasis added by the board). Therefore, this passage concerns the case in which one and the same substance is defined in the claim and in the prior art in different ways. As explained above, the current situation is different since the subject-matter of claim 1 as granted and D49 do not define the same polymorphic form.

4.3 Accordingly, the board saw no deviation in its approach from pertinent case law of the Boards of Appeal and, accordingly, did not consider a decision from the Enlarged Board to be required in the circumstances of the present case. Thus, the board decided not to refer questions to the Enlarged Board and, consequently, to reject the appellant's request to this effect